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Abstract Objective: To analyze the diagnostic accuracy of frozen section pathology and impact factors. Methods: 1091 cases of frozen section diagnosis and conventional histopathologic diagnosis were analyzed. Results: The accuracy of frozen section diagnosis of benign was 96.9% (751/775), borderline 82.8% (24/29), malignant 97.6% (281/288). Conclusion: The frozen section in determining the surgical lesions and selection of reasonable treatment options have significant value.
[KEY WORDS] Frozen section; Pathological diagnosis; Accuracy
select hospital 2003.1 ~ 2005.12 information on 1091 cases of frozen sections, frozen sections made in order to prevent microscopic morphology changes, specimen submission required with a dry gauze wrapped or placed in clean, without any liquid containers timely delivery of Pathology, pathologist detailed examination of the gross specimen obtained after the ########## eye to confirm the most obvious lesions 1 to 2 regional organizations to quickly set automatic constant cold slicer ( UK production SHANDN AS 620E type) on the production sections. Each tissue was cut two slices, thickness 4μm, by the alcohol-fixed, HE staining, normal light microscope (Olympus BX51) under observation,ralph lauren paris, and after 2 to 3 physicians diagnosed group discussion after the film-reading; such as censorship failed Organization ( blood clot, necrosis of exudate, etc.), immediately asked the surgeon a second drawing will be inspected, frozen remnants of tissue for routine paraffin sections, and paraffin sections drawn with the other multiple comparison analysis.
3.1 pathological frozen section diagnosis of lesions of the value of frozen widely used in surgery, surgeons make intraoperative frozen known lesions in the surgery (benign, borderline, malignant),mbt chaussures paris, to determine the appropriate surgical plan. Since 1960 Cryostat frozen microtome in clinical pathology applications, along with improving the quality of pathology technicians and slice the upgrading of equipment, the quality of frozen sections and paraffin sections have almost the same, so that the surgical pathologist in the diagnostic accuracy of frozen section continued increased. Our hospital in recent years imports of large scale investment in freezer-style slicer for the accuracy of frozen section to provide the necessary protection. Therefore, the current rapid frozen section diagnosis and clinical decision an important basis for range operations, the value reflected in the main application: 1. Determine the nature of disease, requiring the pathologist to determine the shortest possible time inspection organization is a non-neoplastic lesions or tumors such as the need to further determine the tumor benign or malignant, because lesions are not typical and can not determine the benign and malignant lesions, then provide a considered opinion or preference for clinical consideration, or to be re-fixed paraffin sections. (2) to determine whether removal of the tumor edge residual tumor tissue. We encounter the most is the implementation of breast-conserving treatment of breast cancer surgery, when the up, down, left, right and base five cutting edge, such as the cutting edge of cancer found, you need to expand the extent of resection, frozen section at this time the results of clinical surgery range has played a decisive role. 3 identify the organization, such as Hirschsprung's disease required surgical margins of the wall confirmed that if there exists myenteric ganglion cells, ganglion cells, such as no longer required to cut the bowel until the investigation, see myenteric ganglion cells so far. 4 to determine the lymph node metastasis, the surgeon determine whether to take the local lymph node metastases to determine the surgical plan, for the existence of pathological lymph node metastasis hidden particularly necessary. 5 head and facial cancer surgery to determine whether the cutting edge of residual tumor tissue removed for cleaning and expand the scope of the direction of the stake, because the head and facial blood vessels, nerve-rich, minor damage will affect the face, so the need for surgery in multiple directions of tissue, to determine whether the residual tumor. Frozen section diagnosis can prevent excessive or inadequate surgery, and some can also avoid unnecessary second operation. It has been reported accuracy rate of frozen sections of 94% to 97% [1,franklin marshall pas cher,2], this group was 96.8%, consistent with the basic literature.


[ABSTRACT] Objective: To analyze the accuracy and effective factors of pathological diagnosis for frozen section pathological diagnosis. Methods: Frozen sections from 1091 cases and routine pathohistological examined result were analyzed. Results: The accuracy of frozen section on benign, inciderline and malignant were 96.9% (751/775), 82.8% (24/29) and 97.6% (281/288) respectively . Conclusion: The results suggest frozen section play an important role in the nature of lesions which was decided and schema of operation was selected.

With increasing levels of clinical surgery, the surgery requires submission of frozen biopsy increasing cases of rapid diagnosis, clinical surgeon dependent on the pathology report also increasing, rapid pathological diagnosis has become frozen in clinical surgeon diagnosis and surgery program must establish a reasonable means. However, in the frozen section surgical pathology affected by many factors, accuracy difficult to achieve with conventional paraffin sections consistent with the results. To this end we collected in our hospital pathology past two years, 1091 cases of frozen sections of data, analysis of the value and accuracy of frozen section diagnosis and its influencing factors, to continuously improve the quality of surgical pathology, thereby reducing the medical risks.
Key words frozen section; pathology; accuracy



1091 例 frozen tissue in 12 systems and organizations, such as the female reproductive system, 485 cases, 44.4% of the total number of cases, 364 cases of breast lesions, accounting for 33.3% , Thyroid 58 cases, accounting for 5.3%, the digestive system in 52 cases, accounting for 4.7% and so on. Submission of the most active departments of gynecology, obstetrics, general surgery followed by other, see Table 1. Table 1 1091 cases of frozen samples in the distribution of the system paraffin confirmed 775 cases of benign lesions, of which 771 cases of frozen meet, frozen 96.9% accuracy rate; paraffin malignant lesions confirmed 286 cases of malignant reported 281 cases of frozen, frozen accuracy rate of 97.6%; paraffin confirmed borderline lesions in 29 cases, frozen borderline report 24 cases of frozen accuracy of 82.8%. 1091 cases of frozen specimens, and paraffin sections in line for the 1056 cases reported, the overall diagnostic accuracy of frozen section was 96.8%,abercrombie paris, misdiagnosed 14 cases, the misdiagnosis rate was 0.13%, Table 2. Table 2 1091 cases of frozen and paraffin diagnosis more
3 Discussion


2 results
1 Materials and methods




1091 cases of surgical pathology diagnostic accuracy of frozen section analysis


Author: rank name Source: Date :04 -11-26 view: times Author: Zhang Jianhong Zhang Fan Chengri Qing Lin Yuanyuan ZHAO Xiu-fang Liu Chao Zhang Jiuhong More articles related to topics：


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